PUBLICATIONS

Pavlik, B.J., E. Hruska, K.E. Van Cott and P. Blum. 2016. Retargeting the Clostridium botulinum C2 toxin to the neuronal cytosol. Scientific Reports 6:23707

Blum, P., D. Rudrappa, R. Singh, S. McCarthy and B. Pavlik. 2016. Experimental Microbial Evolution of Extremophiles. In P.H. Rampelotto (ed.) Biotechnology of Extremophiles: Advances and Challenges.

McCarthy, S., T. Johnson, B. Pavlik, S. Payne, W. Schackwitz, J. Martin, A. Lipzen and P. Blum. 2015. Expanding the Limits of Thermoacidophily in the Archaeon Sulfolobus solfataricus by Adaptive Evolution. Applied and Environmental Microbiology 82(3): 857-67.

Rudrappa, D., A. Yao, D. White, B.J. Pavlik, R. Singh, M.T. Facciotti and P. Blum. 2015. Identification of an archaeal mercury regulon by chromatin immunoprecipitation. Microbiology, 161:2423-33

Ai, C., S. McCarthy, S., W. Schackwitz, J. Martin, A. Lipzen, and P. Blum. 2015. Complete genome sequence of evolved arsenate resistant Metallophaera sedula strains. Genome Announcements 3(5): e01142-15.

Singh, R., J. Gradnigo, D. White, A. Lipzen, J. Martin, W. Schackwitz, E. Moriyama and P. Blum. 2015. Complete Genome Sequence of an Evolved Thermotoga maritima Isolate. Genome Announcements 3(3): e00557-15.

McCarthy, S., J. Gradnigo, T. Johnson, S. Payne, A. Lipzen, J. Martin, W. Schackwitz, E. Moriyama and P. Blum. 2015. Complete genome sequence of Sulfolobus solfataricus strain 98/2 and evolved derivatives. Genome Announcements 3(3): e00549-15.

McCarthy, S., C. Ai, G. Wheaton, R. Tevatia, V. Eckrich, R. Kelly and P. Blum. 2014. Role of an archaeal PitA transporter in the copper and arsenic resistance of Metallosphaera sedula, an extreme thermoacidophile. Journal of Bacteriology 196(20):3562-70.

Schelert, J., D. Rudrappa, T. Johnson and P. Blum. 2013. Role of MerH in Mercury Resistance in Sulfolobus solfataricus. Microbiology 159:1198-208.

Maezato, Y., T. Johnson, S. McCarthy, K. Dana and P. Blum. 2012. Metal Resistance and Lithoautotrophy in the Extreme Thermoacidophile Metallosphaera sedula. Journal of Bacteriology 194(24):6856-6863.

Tevatia, R., Y. Demirel, and P. Blum. 2012. Kinetic modeling of photoautotropic growth and neutral lipid accumulation in terms of ammonium concentration in Chlamydomonas reinhardtii. Bioresource Technology 119:419-424.

Blum, P. 2012. Energy and experience. International Innovation, Environment, June pp. 114-116.

Villafane, A., Y. Voskoboynik, I. Ruhl, D. Sannino1, Y. Maezato, P. Blum and E. Bini. 2011. CopR is a positive regulator of transcription of copper-responsive genes in Sulfolobus solfataricus. Microbiol. 2011 Oct;157(Pt 10):2808-17.

Maezato, Y., K. Dana and P. Blum. 2011. Engineering Thermoacidophilic Archaea Using Linear DNA Recombination. Methods Mol Biol. 765:435-45.

Maezato Y, Daugherty A, Dana K, Soo E, Cooper C, Tachdjian S, Kelly RM, Blum P. 2011. VapC6, a ribonucleolytic toxin regulates thermophilicity in the crenarchaeote Sulfolobus solfataricus. RNA 17(7):1381-92.

Wong JH, Brown JA, Suo Z, Blum P, Nohmi T, Ling H. 2010. Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4. EMBO J. 29:2059-2069.

Friest. J. A., Y. Maezato, S. Broussy, P. Blum and D. B. Berkowitz. 2010. Use of a Robust Dehydrogenase from an Archael Hyperthermophile in Asymmetric Catalysis-Dynamic Reductive Kinetic Resolution Entry into (S)-Profens. J. Am. Chem. Soc. 132:5930-5931.

Miller P. and P. Blum. 2010. Extremophile-Inspired Strategies for Enzymatic Biomass Saccharification. Environmental Technology. 31(8-9):1005-15.

Mandal, D., C. Köhrer, D. Su, S. Russell, K. Krivos, C. Castleberry, P. Blum, P. Limbach, D. Söll, and U. RajBhandary. 2010. Agmatidine, a modified cytidine in the anticodon of archaeal tRNAIle, base pairs with adenosine but not with guanosine. Proc. Natl. Acad. Sci. USA 107:2872-2877.

Maaty, W., B. Wiedenheft, P. Tarlykov, N. Schaff, J. Heinemann, J. Robison-Cox, J. Valenzuela, A. Daugherty, P. Blum, M. Lawrence, T. Douglas, M. Young, and B. Bothner. 2009. Something old, something new, something borrowed; how the thermoacidophilic archaeon Sulfolobus solfataricus responds to oxidative stress. PLoS One. 2009 Sep 16;4(9):e6964

Cooper CR, Daugherty AJ, Tachdjian S, Blum PH, Kelly RM. 2009. Role of vapBC toxin-antitoxin loci in the thermal stress response of Sulfolobus solfataricus. Biochem Soc Trans. 37(Pt 1):123-6.

Auernik, K.S., Maezato, Y., Blum, P., and Kelly, R.M.. 2008. Genome sequence of the metal-mobilizing, extremely thermoacidophilic archaeon Metallosphaera sedula provides insights into bioleaching metabolism. Appl. Environ. Microbiol. 74 682-692. strong>

Blum, P. 2008 (Editor) Archaea, new models for prokaryotic biology. (248 p.) Horizon Press, Norwich UK

Sowers, K. R., P. H. Blum, and S. DasSarma. 2008. Gene transfer in archaea. In, C. A. Reddy, T. J. Beveridge, J. A. Breznak, G. A. Marzluf, and T. M. Schmidt (ed.). Methods for General and Molecular Microbiology. American Society for Microbiology.

Szabo Z, Sani M, Groeneveld M, Zolghadr B, Schelert J, Albers SV, Blum P, Boekema EJ, Driessen AJ. 2007. Flagellar motility and structure in the hyperthermoacidophilic archaeon Sulfolobus solfataricus. J Bacteriol. 189:4305-4309.

Schelert, J., M. Drozda,V. Dixit, A. Dillman and P. Blum. 2006. Regulation of mercury resistance in the crenarchaeote Sulfolobus solfataricus. J Bacteriol. 2006 188:7141-50.

Ernst, H.A., L. L. Leggio, M. Willemoës, G. Leonard, P. Blum|, and Sine Larsen. 2006. Structure of the Sulfolobus solfataricus alpha-glucosidase: Implications for domain conservation and substrate recognition in GH31. J. Molec. Biol. 358:1106-1124.

Blum, P. 2006. Understanding Viability of Pathogens During Disinfection, 00-HHE-1. Water Env. Fed. pp 1- 65.

Ernst, H.A., Willemoës, M., Lo Leggio, L., Leonard, G., Blum, P., and Larsen, S. 2005. Crystallization and preliminary crystallographic characterization of the a-glucosidase MalA from Sulfolobus solfataricus. Acta Cryst. F61:1039-1042.

Simbahan, J., E. Redfield, and P. Blum. 2005. Community analysis of a mercury hot spring supports occurrence of domain-specific forms of mercuric reductase. Appl. Environ. Microbiol. 71:8836-8845.

Hoang, V., E. Bini, V. Dixit, M. Drozda, and P. Blum. 2004. The role of cis-acting sequences governing catabolite repression control of lacS expression in the archaeon Sulfolobus solfataricus. Genetics. 167: 1563-1572.

Simbahan, J., R. Drijber, and P. Blum. 2004. Alicyclobacillus vulcanalis sp. nov., a new thermophilic, acidophilic bacterium isolated from Coso Hot Springs, California, USA. Int. J. Syst. Evol. Microbiol. 54: 1703-1707

Korencic, D., I., Ahel, J., Schelert, M., Sacher, B., Ruana, C., Stathopoulosa, P., Blum, M., Ibba, and D. Söll. 2004. A freestanding proofreading domain is required for protein synthesis quality control in Archaea. Proc. Natl. Acad. Sci. USA 101:10260-10265.

Chen, H., G. Ponniah, N. Solanen, and P. Blum. 2004. Culture-independent analysis of fecal enterobacteria in environmental samples by single cell mRNA profiling. Appl. Environ. Microbiol. 70:4432-4439.

Dixit, V., M. Drozda, E. Bini and P. Blum. 2004. Mecury targets transcription in the archaeon Sulfolobus solfataricus. Antimicrob. Agents Chemother. 48:1993-1999.

Schelert, J., V. Dixit, V. Hoang, J. Simbahan, M. Drozda and P. Blum. 2004. Occurrence and characterization of mercury resistance in the hyperthermophilic archaeon Sulfolobus solfataricus using gene disruption. J. Bacteriology 186:427-437.

Sowers, K. R., P. H. Blum, and S. DasSarma. 2004. Genetics of Archaea in "Methods for General and Molecular Microbiology" ASM Press. Washington D.C. (In Press).

Ponniah, G., H. Chen, R. Michielutti, N. Salonen and P. Blum. 2003. Single cell protein profiling of wastewater enterobacterial communities predicts disinfection efficiency. Appl. Environ. Microbiol. 69:69:4227-4235.

Worthington, P., V. Hoang, P. Perez-Pomares, and P. Blum. 2003. Targeted disruption of the "-amylase gene in the hyperthermophilic archaeon Sulfolobus solfataricus. J. Bacteriol. 185:482-488.  

Worthington, P., P. Blum, F. Perez-Pomares, and T. Elthon. 2003. Large scale cultivation of acidophilic hyperthermophiles for recovery of secreted proteins. Appl. Environ. Microbiol. 69:252-257.

Bini, E., V. Dikshit, K. Dirksen, M. Drozda, and P. Blum. 2002. Stability of mRNA in hyperthermophilic archaea. RNA 8:1129-1136.

Blum, P. and V. Dikshit. 2002. Archaea. In “Desk Encyclopedia of Microbiology”, M. Schaechter (ed). Academic Press, New York

Blum, P. 2001. (Ed.), Archaea, ancient microbes, extreme environments and the origin of life. Adv. Appl. Microbiol. vol. 50, pp. 1-382. Academic Press, New York

Bini, E., and P. Blum. 2001. Archaeal catabolite repression: a gene regulatory paradigm. Adv. Appl. Microbiol. 50: 339-366.

Haseltine C, Hill T, Montalvo-Rodriguez R, Kemper SK, Shand RF, Blum P. 2001. Secreted euryarchaeal microhalocins kill hyperthermophilic crenarchaea. J. Bacteriol. 183:287-91.

Montalvo-Rodriguez R, Haseltine C, Huess-LaRossa K, Clemente T, Soto J, Staswick P, Blum P. 2000. Autohydrolysis of plant polysaccharides using transgenic hyperthermophilic enzymes. Biotechnol Bioeng. 70:151-9.

Rockabrand, D., T. Austin, R. Kaiser, and P. Blum. 1999. Bacterial growth state by single-cell protein profiling: does chlorination kill coliforms in municipal effluent? Appl. Environ. Microbiol. 65:4181-4188.

Haseltine, C., R. Montalvo-Rodriguez, A.Carl, E. Bini and P. Blum. 1999. Extragenic Pleiotropic Mutations That Repress Glycosyl Hydrolase Expression in the Hyperthermophilic Archaeon Sulfolobus solfataricus. Genetics 152:1353-1361.

Haseltine, C., R. Montalvo-Rodriguez, E. Bini, A. Carl, and P. Blum. 1999. Coordinate transcriptional control in the hyperthermophilic archaeon Sulfolobus solfataricus. J. Bacteriol. 181:3920-7.

Teter, S., W. Houry, D. Ang, T. Tradler, D. Rockabrand, G. Fischer, P. Blum, C. Georgopoulos, and F. Hartl. 1999. Polypeptide flux through bacterial Hsp70: DnaK cooperates with trigger factor in chaperoning nascent chains. Cell 97:755-65.

Whitman, W. B., F. Pfeifer, P. Blum and A. Klein. 1999. What archaea have to tell biologists. Genetics 152:1245-1248.

Rockabrand, D., K. Livers, T. Austin, R. Kaiser, D. Jensen, R. Burgess, and P. Blum. 1998. Roles of DnaK and RpoS in starvation-induced thermotolerance of Escherichia coli. J. Bacteriol. 180:846-854.

Rolfsmeier, M., C. Haseltine, E. Bini, A. Clark, and P. Blum. 1998. Molecular Characterization of the alpha-Glucosidase Gene (malA) From the Hyperthermophilic Archaeon Sulfolobus solfataricus. J. Bacteriol. 180:1287-1295.

Lund, A. A., P. H. Blum and T. E. Elthon. 1998. Heat stress response of maize mitochondria. J. Plant Physiol. 116:1097-1110.

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Blum, P. H. 1997. Molecular genetics of the bacterial stationary phase. In "Bacteria in the Oligotrophic Environment, with Special Emphasis on Starvation Survival" by R. Morita. Chapman and Hall.

Haseltine, C., M. Rolfsmeier, and P. Blum. 1996. The glucose effect and regulation of -amylase production in the hyperthermophilic archaeon Sulfolobus solfataricus. J. Bacteriol 178:945-950.

Rockabrand, D. and P. Blum. 1995. Multicopy plasmid supression of stationary phase chaperone toxicity in Escherichia coli by phosphogluconate dehydratase and the N-terminus of DnaK. Mol. Gen. Genet. 249:498-506.

Bailey, S.M., P. Blum, and M.M. Meagher. 1995. Improved Homogenization of Recombinant Escherichia coli Following Pretreatment With Guanidine HCl. Biotechnol. Prog. 11:533-539.

Rolfsmeier, M., and P. Blum. 1995. Purification and characterization of a maltase from the extremely thermophilic Crenarchaeote Sulfolobus solfataricus. J. Bacteriol. 177:482-485.

Krska, J., T. Elthon, and P. Blum. 1993. Monclonal antibody recognition and function of a DnaK (HSP70) epitope found in gram negative bacteria. J. Bacteriol. 175:6433-6440.

Rockabrand, D., J. Partridge, and P. Blum. 1993. Nucleotide sequence analysis and heterologous expression of the Erysipelothrix rhusiopathiaednaJ gene. FEMS Microbiol. Lett. 111:79-86.

Partridge, J., J. King, D. Rockabrand and P. Blum. 1993. Cloning, molecular analysis and expression of the Erysipelothrix rhusiopathiae dnaK gene. Infection and Immunity 61:411-417.

Blum, P., J. Bauernfiend, J. Ory, and J. Krska. 1992. Physiological consequences of DnaK and DnaJ overproduction in Escherichia coli. J. Bacteriol. 174:7436-7444.

Blum, P., M. Velligan, N. Lin and A. Matin. 1992. Dissagregation and solubilization of Human Growth Hormone inclusion bodies by DnaK. Bio/technology 10:301-304.